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SyZygy cubensis strain is very potent. The SyZygy does live up the hype with plenty of potencies in dense medium-sized fruits over multiple prolific flushes. Definitely a great strain for any serious collector. Syzygy Shroom Strain: A Potent Strain Discovered by the Famed Terence McKennaThis strain comes straight out of Terence McKenna’s private stash.Dan SimmsLast Updated: July 09, 2022PrintSome magic mushroom strains are popular because of their super-high potency, and others make headlines for the massive size of their fruiting bodies. The Syzygy strain, however, is most famous for having been discovered, isolated, and sold by Terence McKenna, regarded by many as one of the godfathers of psychedelics.In this ultimate guide to the Syzygy strain, we’ll discuss the strain’s history, potency, and where to buy spores. We’ll also briefly cover how to cultivate this strain and which other varieties you can check out if you enjoy growing or consuming this one.What Are Syzygy Shrooms?The Syzygy strain is a variety of magic mushrooms that falls under the scientific classification of Psilocybe cubensis. The original sample was allegedly collected in the Amazon in South America by Terence McKenna — perhaps the most famous psychonaut in history.The Syzygy strain is best known for being the first strain McKenna sold spore samples for via an online store he named after this strain — or, perhaps, vice versa. Unfortunately, some of the samples he collected and sold are no longer available anywhere, and the Syzygy strain is one of the few that remains. The Syzygy strain is known for having an average potency, although many users report that the trip experience is more intense and introspective than the potency would suggest.Syzygy Shroom Specs:Potency AverageCultivation BeginnerSpecies Psilocybe cubensisSubstrate Recommendation Rye Grain or Brown Rice FlourCost $Sold By Ralphsters Spores, Free Spores, Lil Shop of SporesStrains vs. Species: What’s The Difference?The term “strain” refers to a unique variety of plants or mushrooms within a given species. Species refer to all members of related specimens that can reproduce together. Two members from different species cannot reproduce viable offspring. When we talk about strains of magic mushrooms, we’re normally referring to unique varieties contained within the greater Psilocybe cubensis species. Syzygy Shrooms Potency & Psilocybin ContentThe Syzygy strain is known for having an average potency. While there isn’t enough analytical information to provide an accurate average — based on the reported potency of this shroom, we estimate the total tryptamine content is somewhere between 0.6% and 0.1.2%. The total tryptamine levels refer to the combined percentage of both psilocybin and psilocin, along with a few other trace tryptamine derivatives. Where to Buy Syzygy Shroom SporesIf you live in the United States, you can purchase Syzygy spores from Ralphster’s Spores, Free Spores, or Lil Shop of Spores.If you live in Canada, you can check Spores 101, although this strain was not available there as of this writing.Finally, if you live in Europe, you’ll likely have some difficulty finding this strain. You can check places like The Magic Mushroom Shop and Viking Spore, but this strain isn’t always available from those vendors.There are also spore trading circles in most parts of the world where hobbyists get together and trade spores amongst each other. This is a great place to find some of the more rare or exotic strains like Syzygy.Related: How & Where to Buy Magic Mushroom Spores (Legally).How to Grow Syzygy ShroomsLike most cubes, growing the Syzygy strain is relatively straightforward and just takes some attention when it comes to sterilizing your substrate, equipment, and workspace. The Syzygy strain isn’t known to be a particularly fast colonizer, so it’s somewhat sensitive to mold and contamination. However, with the proper setup, this strain should be suitable for beginners and experienced cultivators alike.Syzygy shrooms hail from a pantropical climate, so you can likely get away with some variance in your humidity levels and the temperatures in your incubator and fruiting chamber. Still, sticking to the standards will be best and will give you the greatest chance for success.This strain is a dense fruiter, so although the fruiting bodies are small to medium-sized, you should get a decent harvest from each grow over three to four flushes.For an in-depth discussion on how to grow the Syzygy strain, you can read through our guide on cultivating magic mushrooms.Similar StrainsThe Syzygy strain is highly sought-after, mainly because it was discovered by the legendary Terence McKenna himself. Unfortunately, it can sometimes be challenging to find these spores, even from the larger vendors in the US, Canada, and Europe. Here are some of the best alternatives to consider instead: 1. Mazatapec ShroomsThe Mazatapec strain was originally collected in Mexico, and it’s another variety that was discovered and isolated by Terence McKenna. For this reason, it’s a great alternative to the Syzygy strain if you’re looking for something with a similar history. This strain is relatively easy to cultivate and has a higher potency than the Syzygy strain.2. Melmac ShroomsThe origins of the original sample of the Melmac strain are debatable, but it’s believed to have been collected by Terence McKenna. It’s a straightforward strain to grow, as it colonizes quickly and has good resistance to mold. This strain has a very high potency, and it’s probable that it’s very closely related to the Penis Envy strain, which is considered the most potent cubensis strain.3. Penis Envy ShroomsAs mentioned above, the Penis Envy strain is likely related to the Melmac strain, which was one of McKenna’s discoveries. Many people believe that the Penis Envy strain was developed from a sample collected by McKenna as well, although the details are a bit fuzzy. Steven Pollock is credited with isolating the strain we know and love today, possibly from a sample collected during the famed McKenna shroom expeditions.4. Amazon ShroomsThe Amazon strain — also called the P.E.S. strain or the PESA strain — was originally collected and isolated by the Hawaiian spore company Pacifica Exotica Spora, hence the abbreviated name. It hails from the Amazon, as the name suggests, so it has a lot in common with the Syzygy strain. Many people actually believe that the two are almost identical and were just collected at different times by two different foragers.5. Golden Teacher ShroomsGolden Teachers are one of the most popular strains because they offer a well-balanced and rarely-overwhelming trip experience. The same can be said for the Syzygy strain, so this is a popular and much more widely available alternative for those looking for a similar psychedelic experience to the Syzygy strain.Final Thoughts: Syzygy ShroomsThe Syzygy strain is a variety of magic mushrooms that is best known for having been discovered and isolated by Terence McKenna. It’s native to the Amazon in South America, and it’s one of the first strains that was ever sold on McKenna’s spore website. It’s believed to be closely related to the Amazon strain and several others that are native to South America.The Syzygy strain is relatively resistant to contaminants, so it’s a great option for beginner cultivators. It also provides a well-balanced psychedelic experience, similar to Golden Teachers, and it’s a favorite among new and experienced psychedelic mushroom users.